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IDEX MPT Equipment for Biopharma

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Drug Delivery

Effective drug carriers allow targeted delivery, improve absorption, and reduce side effects, while also supporting controlled release. Manufacturers must address challenges of particle size control, sterilization, scalability, and regulatory compliance. Microfluidizer® technology produces uniform nanoparticles, ensuring consistent absorption, superior quality, and extended shelf-life.

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Biopharma Applications

Microfluidizer® high shear fluid processors deliver reliable results, ensuring precise submicron particle size reduction, uniform dispersion, cell disruption, and exceptionally tight particle size distributions. Trusted across the biopharma industry, these high-pressure processors support manufacturers and researchers in securing consistent product quality and process efficiency.

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Scale Up

Microfluidizer® technology is capable of seamlessly scaling outcomes from the laboratory to pilot and full production volumes. Scale up is achieved thanks to the Interaction Chamber™ in each model that ensures results achieved in the lab are reliably reproduced at every stage. Microfluidics supports customer scale-up with expert process knowledge and proven technology.
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Why Us

Across the IDEX MPT group, we are specialists in high shear liquid and particle processing. Our brands are recognized for offering well-designed equipment solutions to leading biopharma manufacturers. Driven by the IDEX values of trust, team, and excellence, our teams utilize creative problem-solving and collaboration to guide our global customers towards their objectives.

Each product in our portfolio is designed and manufactured to high standards of materials, finish, and performance. Our equipment is efficient, reliable, and compliant with the strict industry standards, so you can trust in our brands to deliver safe, durable solutions with a high return on investment.

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Global Coverage

Multiple locations around the world allow us to serve customers globally.

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Integrated Teams

The IDEX MPT brands are united to provide you with comprehensive solutions.

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Trusted Solutions

Our brands are tested, used & trusted by leading manufacturers worldwide.

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Years of Expertise

Many of our brands have been providing pharmaceutical solutions for over 40 years.

Microfluidizer® Technology

Microfluidizer® technology consistently delivers small and uniform nanoparticles, enhancing absorption, content uniformity, and product shelf-life. Microfluidics differentiates itself from its competition in its unparalleled ability to achieve superior, repeatable results with seamless, linear scale-up capabilities.

At the heart of our success — and our customers' — is our unique fixed-geometry Interaction Chamber™. Only Microfluidizer® processors feature this crucial component, which ensures that every milliliter of product experiences virtually identical shear forces under extreme, user-controlled pressure. This enables precise, consistent processing—often achieved in just one or two passes.

How Microfluidizer® Processors Work

Formulating Drug Delivery Systems

Equipment for the formulation of nanoemulsions, LNPs, liposomes, nanoparticle albumin bound (Nab), and more.

Effective drug delivery systems are essential in the development of modern pharmaceuticals, including gene therapies, cancer treatments, and vaccines. By safeguarding and accurately transporting therapeutic agents, advanced drug carriers ensure targeted delivery and controlled drug release for optimal absorption. These carriers offer key benefits such as improved bioavailability, enhanced biodegradability, precise release timing, and consistent absorption at the intended site.

To achieve these capabilities, particle sizes and distributions must be tightly controlled and, in certain cases, the equipment used needs to offer aseptic processing. Repeatability and scalability are also a must when scaling results achieved during research and development to wider manufacturing.

Microfluidics, a brand within IDEX MPT, offers high shear fluid processing with its range of Microfluidizer® processors. This technology offers a precise and scalable solution for formulating drug delivery systems, with processors for lab, pilot, and production scale.

Drug Delivery Systems

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Drug Delivery Applications

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Liposomes

Liposomes are highly adaptable drug delivery systems made from lipid bilayers that can transport a wide range of pharmaceutical ingredients. They are biocompatible and allow for the delivery of different drugs at the same time. Producing consistent, high-quality liposomes with high drug loading remains a challenge. Microfluidizer® technology addresses this with rapid vesicle size reduction and reliable scale up, even at high therapeutic concentrations.

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Nab-paclitaxel

Nab technology offers a safer, biocompatible way to deliver chemotherapy drugs, reducing side effects compared to traditional carriers. Accurate control of particle size and manufacturing consistency ensures the production of reliable, stable nanoemulsions for nab-paclitaxel. Microfluidizer® technology delivers precisely controlled high shear forces, enabling reliable scale-up and sterile filtration for high-quality drug delivery.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Polymer Nanoparticles

Polymer nanoparticles are an advanced drug delivery system, valued for their ability to carry various active ingredients, target specific sites, control ingredient release, and protect against degradation. They are produced by forming and solidifying small emulsion droplets that encapsulate the drug. To reliably meet demand, Microfluidizer® processors provide precise control over particle size, allow for terminal sterilization, and offer easy cleaning.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Nanoemulsions

Nanoemulsions with stable, uniform particle sizes are essential for drug delivery systems, enhancing sterility, bioavailability, and stability. Microfluidics® technology ensures consistent high shear processing for precise nanoemulsion quality at any scale. With over 40 years of experience, Microfluidizer® processors offer easy and reliable nanoemulsion production that scales smoothly from research to full commercial manufacturing.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Lipid Nanoparticles

Lipid nanoparticles (LNPs) enable the precise delivery of genetic materials, supporting the advancement of next-generation vaccines and gene therapies. Comprised of specialized lipids, cholesterol, and PEG lipid, LNPs safely transport proteins and nucleic acids to targeted sites. Microfluidizer® technology ensures consistent, stable LNP production that can scale results precisely, making the process efficient and reliable.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

Biopharma Applications

Microfluidics offers a complete range of Microfluidizer® processors for biopharmaceutical applications.

With decades of experience and deep industry expertise, Microfluidics is a trusted global leader in biopharma manufacturing equipment.

Microfluidizer® processors are purpose-built for pharmaceutical and biotech use, allowing manufacturers to meet regulatory standards. They reliably deliver consistent results in nanoemulsions, suspensions, cell disruption, and lipid nanoparticle production—making advanced processing efficient and reliable.

Our high-quality solutions are relied upon in FDA-approved drug production worldwide, delivering superior particle size reduction and optimal yields for biotech and pharmaceutical applications.

Equipment for Biopharma Applications

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Key Biopharma Applications

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Lipid Nanoparticles

Lipid nanoparticles (LNPs) enable the precise delivery of genetic materials, supporting the advancement of next-generation vaccines and gene therapies. Comprised of specialized lipids, cholesterol, and PEG lipid, LNPs safely transport proteins and nucleic acids to targeted sites. Microfluidizer® technology ensures consistent, stable LNP production that can scale results precisely, making the process efficient and reliable.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Cell Disruption

Cell disruption is a crucial step in extracting valuable intracellular components, where maintaining the integrity of these materials is essential for product quality. Microfluidics technology enables efficient cell disruption to release and preserve valuable intracellular materials, ensuring easy downstream purification. This not only enhances process consistency but also supports scalable, high-throughput operations for demanding applications.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Nanoemulsions

Nanoemulsions with stable, uniform particle sizes are essential for drug delivery systems, enhancing sterility, bioavailability, and stability. Microfluidics® technology ensures consistent high shear processing for precise nanoemulsion quality at any scale. With over 40 years of experience, Microfluidizer® processors offer easy and reliable nanoemulsion production that scales smoothly from research to full commercial manufacturing.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

Scale Up

Reliably transferring results from lab scale to pilot and production.

Microfluidizer® technology ensures consistent results at every stage—from lab testing to pilot trials and full-scale production. This seamless scale-up is critical for pharmaceutical manufacturing, supporting process reliability, optimal production rates, and fewer product defects.

Microfluidizer® processors feature parallel-aligned microchannels within the Interaction Chamber™, guiding the entire product stream through the same precise conditions. This guarantees uniform shear and consistent quality, whether processing 1ml or thousands of liters.

Scaling Up Results

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Processors for Lab, Pilot and Production Scale

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Lab Scale

Microfluidizer® benchtop processors offer a compact design, simple installation, convenience, ease of use, and easy maintenance. This allows you to scale up smoothly and maintain consistent, repeatable results in every batch with unmatched versatility.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Pilot Scale

Microfluidics pilot scale processors are capable of processing small volumes, making them ideal for running both R&D and pilot-scale batches. Regardless of sample size, footprint or operating temperature/pressure, all Microfluidizer® processors excel at treating every mL of your product the same every time.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

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Production Scale

Scale-up to production manufacturing is seamless for all applications. The M700 is a proven, cost-effective choice that withstands high-demand production environments. In 2023, Microlyser™ technology was introduced, combining our proprietary Interaction Chamber™ with a patented pumping system.

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with a request body that specifies how to map the columns of your import file to the associated CRM properties in HubSpot.... In the request JSON, define the import file details, including mapping the spreadsheet's columns to HubSpot data. Your request JSON should include the following fields:... entry for each column.

The IDEX MPT Brands